CLSI M100 S18 PDF

Access M and M60 Free. This guideline discusses the necessary and recommended data for selecting appropriate breakpoints and quality control ranges for antimicrobial agents. Download M Access VET08 Free. Download EP

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Objectives: In , a new set of penicillin breakpoints was published in the CLSI revised guideline, MS18, to define the susceptibility of non-meningeal isolates of Streptococcus pneumoniae. The impact of the change is studied and discussed. Methods: Laboratory data on pneumococcal isolates collected from Chang Gung Memorial Hospital during were analysed using the original and modified penicillin CLSI breakpoints. Results: A total of non-duplicate isolates were identifed, including 43 1.

For non-meningeal isolates, penicillin non-susceptibility was reduced significantly from Ceftriaxone non-susceptibility also increased significantly from 2. A quarter Higher resistance to penicillin Conclusions: With the implementation of the new breakpoints, clinicians may continue to use penicillin for the treatment of non-meningeal pneumococcal infections in preference to other drug classes.

However, as isolates with borderline penicillin MICs are increasing, continued surveillance of pneumococcal susceptibility to penicillin will be needed. This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search. Advanced Clipboard.

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Save Cancel. Create a file for external citation management software Create file Cancel. Full-text links Cite Favorites. Abstract Objectives: In , a new set of penicillin breakpoints was published in the CLSI revised guideline, MS18, to define the susceptibility of non-meningeal isolates of Streptococcus pneumoniae.

Similar articles New penicillin susceptibility breakpoints for Streptococcus pneumoniae and their effects on susceptibility categorisation in Germany Int J Antimicrob Agents. Epub May 5. PMID: Effects of new penicillin susceptibility breakpoints for Streptococcus pneumoniae--United States, Impact of the revised penicillin susceptibility breakpoints for Streptococcus pneumoniae on antimicrobial resistance rates of meningeal and non-meningeal pneumococcal strains.

Al-Waili BR, et al. Ann Saudi Med. Rationale for revised penicillin susceptibility breakpoints versus Streptococcus pneumoniae: coping with antimicrobial susceptibility in an era of resistance. Weinstein MP, et al. Clin Infect Dis. PMID: Review. Therapeutic options for pneumococcal pneumonia in Turkey. Oncu S, et al. Clin Ther. Show more similar articles See all similar articles.

Wang CC, et al. Medicine Baltimore. Clinical Trial. Penicillin susceptibility breakpoints for Streptococcus pneumoniae and their effect on susceptibility categorisation in Germany Epub Jun Antimicrobial susceptibility among Gram-positive organisms collected from pediatric patients globally between and results from the Tigecycline Evaluation and Surveillance Trial.

Brandon M, Dowzicky MJ. Brandon M, et al. J Clin Microbiol. Epub May Publication types Research Support, Non-U. Gov't Actions. Child Actions. Child, Preschool Actions. Hospitals, University Actions. Humans Actions. Infant Actions. Taiwan Actions. Treatment Outcome Actions.

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The standards contain information about both disk M2 and dilution M7 test procedures for aerobic bacteria. Clinicians depend heavily on information from the clinical microbiology laboratory for treatment of their seriously ill patients. The clinical importance of antimicrobial susceptibility test results requires that these tests be done under optimal conditions and that laboratories have the capability to provide results for the newest antimicrobial agents. The tabular information presented here represents the most current information for drug selection, interpretation, and quality control using the procedures standardized in M2 and M7. Users should replace the tables published earlier with these new tables.

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