Access M and M60 Free. This guideline discusses the necessary and recommended data for selecting appropriate breakpoints and quality control ranges for antimicrobial agents. Download M Access VET08 Free. Download EP
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Objectives: In , a new set of penicillin breakpoints was published in the CLSI revised guideline, MS18, to define the susceptibility of non-meningeal isolates of Streptococcus pneumoniae. The impact of the change is studied and discussed. Methods: Laboratory data on pneumococcal isolates collected from Chang Gung Memorial Hospital during were analysed using the original and modified penicillin CLSI breakpoints. Results: A total of non-duplicate isolates were identifed, including 43 1.
For non-meningeal isolates, penicillin non-susceptibility was reduced significantly from Ceftriaxone non-susceptibility also increased significantly from 2. A quarter Higher resistance to penicillin Conclusions: With the implementation of the new breakpoints, clinicians may continue to use penicillin for the treatment of non-meningeal pneumococcal infections in preference to other drug classes.
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Save Cancel. Create a file for external citation management software Create file Cancel. Full-text links Cite Favorites. Abstract Objectives: In , a new set of penicillin breakpoints was published in the CLSI revised guideline, MS18, to define the susceptibility of non-meningeal isolates of Streptococcus pneumoniae.
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Brandon M, Dowzicky MJ. Brandon M, et al. J Clin Microbiol. Epub May Publication types Research Support, Non-U. Gov't Actions. Child Actions. Child, Preschool Actions. Hospitals, University Actions. Humans Actions. Infant Actions. Taiwan Actions. Treatment Outcome Actions.
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The standards contain information about both disk M2 and dilution M7 test procedures for aerobic bacteria. Clinicians depend heavily on information from the clinical microbiology laboratory for treatment of their seriously ill patients. The clinical importance of antimicrobial susceptibility test results requires that these tests be done under optimal conditions and that laboratories have the capability to provide results for the newest antimicrobial agents. The tabular information presented here represents the most current information for drug selection, interpretation, and quality control using the procedures standardized in M2 and M7. Users should replace the tables published earlier with these new tables.