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Fordyce angiokeratoma is a benign skin neoplasm, characterized by erythematous-violet keratotic papules with mamillated surface, which follows a chronic and minimally symptomatic course. However, symptoms can be related such as itching, burning, bleeding, dyspareunia; aesthetic and social concerns may prompt request for treatment. The condition mainly affects men and usually occurs in the scrotum, but rarely may occur in women. A year-old woman with liver cirrhosis and portal hypertension is described.
Over a period of two years she developed multiple angiokeratomas of the vulva, complicated by frequent bleeding. Histopathologic analysis of the lesion confirmed the diagnosis of angiokeratoma and all lesions were surgically removed. The results of the treatment were very satisfactory, with no relapses or complications. Skip to main content. UC Davis. Email Facebook Twitter.
Abstract Fordyce angiokeratoma is a benign skin neoplasm, characterized by erythematous-violet keratotic papules with mamillated surface, which follows a chronic and minimally symptomatic course. Thumbnails Document Outline Attachments. Highlight all Match case. Whole words. Toggle Sidebar. Zoom Out. More Information Less Information. Enter the password to open this PDF file:.
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Dermatology Online Journal
Angiokeratoma is a condition in which small, dark spots appear on the skin. They can appear anywhere on your body. These lesions happen when tiny blood vessels called capillaries dilate, or widen, near the surface of your skin. They can be mistaken for a rash, skin cancer , or a condition like genital warts or herpes. Angiokeratomas can sometimes be a symptom of an underlying condition, such as the rare genetic disorder known as Fabry disease FD. You may need to see a doctor for treatment to prevent complications. The exact shape, size, and color can vary.
Angiokeratoma is a benign cutaneous lesion of capillaries, resulting in small marks of red to blue color and characterized by hyperkeratosis. Angiokeratoma corporis diffusum refers to Fabry's disease ,  but this is usually considered a distinct condition. Presentation includes telangiectasia , acanthosis , and hyperkeratosis. Presentation can be solitary or systemic. Multiple angiokeratomas, especially on the trunk in young people, are typical for Fabry disease , genetic disorder connected with systemic complications. In some instances nodular angiokeratomas can produce necrotic tissue and valleys that can harbor fungal, bacterial and viral infections. Infections can include staphylococcus.
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