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Ethnopharmacological relevance: Cordia ecalyculata Vell. Micheli are extensively used in Brazil as therapeutic preparations for indigenous groups and the general population. These plants have been used in the folk medicine as: tonic, diuretic, anti-inflammatory, appetite suppressants, for the treatment of snake bites, and weight loss. Aim of the study: In this study, it was verified the possible cytotoxic and genotoxic effects of the crude extracts of.

Cordia ecalyculata and Echinodorus grandiflorus, as well as their effectiveness in treating obesity. Materials and methods: The Micronucleus Test was used for the evaluation of possible clastogenic and aneugenic effects, and the Comet Assay was used for the evaluation of single-strand and double-strand DNA breaks.

Swiss mice Mus musculus were used as the experimental model. Conclusion: The results of this study allowed us to infer that the crude extracts of Cordia ecalyculata and Echinodorus grandiflorus do not display cytotoxic or genotoxic activities.

However, they do possess weak clastogenic activity without significance on peripheral blood cells. Contrary to commonly held beliefs it was also found in this study that the extracts are not effective for obesity treatments. This site needs JavaScript to work properly.

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J Ethnopharmacol. Epub Nov 6. PMID: Mutagenic potential of Cordia ecalyculata alone and in association with Spirulina maxima for their evaluation as candidate anti-obesity drugs. Araldi RP, et al. Genet Mol Res. Antiedematogenic activity and phytochemical composition of preparations from Echinodorus grandiflorus leaves.

Garcia Ede F, et al. Epub Jul Echinodorus grandiflorus: Ethnobotanical, phytochemical and pharmacological overview of a medicinal plant used in Brazil. Marques AM, et al. Food Chem Toxicol. Epub Mar PMID: Review.

Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.

Int J Toxicol. Show more similar articles See all similar articles. Carvalho-Silva R, et al. Evid Based Complement Alternat Med. Epub Mar 6. Portella VG, et al. Nephron Extra. Epub Jun Do herbal medicines have potential for managing snake bite envenomation?

Gupta YK, et al. Toxicol Int. Publication types Comparative Study Actions. Research Support, Non-U. Gov't Actions. Animals Actions. Male Actions. Mice Actions. Plant Leaves Actions. Substances Cytotoxins Actions. Plant Extracts Actions. Full-text links [x] Elsevier Science. Copy Download.


Cordia ecalyculata Vell.



Cordia ecalyculata



Autonyms (not in current use), synonyms and invalid designations:




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